Institute for Molecular Medicine

연구 업적

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고려대학교 의과대학 생화학분자생물학교실 소속 저자가 포함된 최근 5년 PubMed 논문 목록 (최근 갱신: 2026-10-23)

굵은 글씨는 교실 소속 저자입니다.

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  1. 1

    Multivalent protein nanocages improve the safety profile of cluster of differentiation 47 checkpoint blockade

    Ahn W, Kim S, Lee Y, Chae J, Park D, Chang KH, Lee P, Cho S, ..., Lee EJ

    Int J Biol Macromol, 2026 DOI PMID 42849672

  2. 2

    Authors' response to "Circulating engagement or intrarenal action in signal regulatory protein α-engineered mesenchymal stem cell-derived extracellular vesicle therapy for acute kidney injury?"

    Shin DU, Jo MK, Kwon M, Lee JP, Kim IS, Lee J, Nam GH

    Kidney Int, 2026 DOI PMID 42624550

  3. 3

    Vitreous humor-mimetic liposomes enable effective gene delivery to the eye via intravitreal injection

    Choi SY, Cho CS, Kim S, Kim JH, Kim H, Kim KH, Jo DH, Lee H

    Biomaterials, 2026 DOI PMID 42066435

  4. 4

    Extracellular vesicle-mediated HIF-1α delivery promotes durable vascular remodeling via endothelial Dll1-dependent CD163+ macrophage differentiation

    Cho S, Lee Y, Hwang YH, Goo J, Han J, Woo J, Nam GH, Jeong C, Kim I, Kim IS

    J Control Release, 2026 DOI PMID 41887468

  5. 5

    Neonatal Fc receptor (FcRn)-targeted design of protein nanocages for sustained circulation

    Lee Y, Kang D, Ahn W, Kwon S, Hu Y, Kim N, Go Y, Shin KH, Lee EJ

    Int J Biol Macromol, 2026 DOI PMID 41881225

  6. 6

    Engineering NKG2D ligand affinity transforms EGFR-targeted NK cell engagers into high-potency effectors against pancreatic cancer

    Lee SG, Lee M, Lee HM, Son GH, Yoon SR, Chae BH, Kim DS, Lee KM, Kim YS

    J Biol Eng, 2026 DOI PMID 41808148

  7. 7

    Stimuli-Responsive Hydrogels: From Swelling-Deswelling Mechanisms to Biomedical Applications

    Kim MK, Lee J, Kang AR

    Nanomaterials (Basel), 2026 DOI PMID 41823780

  8. 8

    The Evolution of Nanoparticle Regulation: A Meta-Analysis of Research Trends and Historical Parallels (2015-2025)

    Shin SK, Sharma N, An SSA, Kim MJ

    Nanomaterials (Basel), 2026 DOI PMID 41591051

  9. 9

    Saccharomyces cerevisiae-Fermented Salmon Placental Protein Inhibits Muscle Loss in a Mouse Model of Sarcopenia

    Lee JC, Lim TJ, Lee HM, Jun SM, Lee KM

    Food Sci Nutr, 2025 DOI PMID 41473400

  10. 10

    Therapeutic reprogramming of circulating myeloid cells via signal regulatory protein α extracellular vesicles in acute kidney injury

    Shin DU, Jo MK, Kwon M, Jeong Y, Cho B, Kim SA, Choi GE, Kim S, ..., Nam GH

    Kidney Int, 2025 DOI PMID 41448459

  11. 11

    The E2F1-HMGCR axis promotes ferroptosis resistance in immune refractory tumor cells

    Son SW, Lee HJ, Kang N, Bae S, Cho E, Kwon H, Yoon DY, Lee C, ..., Song KH

    Nat Commun, 2025 DOI PMID 41339438

  12. 12

    Breaking barriers: Engineering extracellular vesicles for enhanced endosomal escape and therapeutic delivery

    Kim J, Hwang YH, Nam GH, Kim IS

    J Control Release, 2025 DOI PMID 41285243

  13. 13

    BOGO: A Proteome-Wide Gene Overexpression Platform for Discovering Rational Cancer Combination Therapies

    Jo KB, Alruwaili MM, Kim DE, Koh Y, Kim H, You K, Kim JS, Sane S, ..., Kim DK

    bioRxiv, 2025 DOI PMID 40950237

  14. 14

    Systemic chemotherapy in metastatic TNBC polarizes effector T cell differentiation

    Ju HY, Yoon H, Jung S, Park SI, Kim TK, Han MR

    Cancer Cell Int, 2025 DOI PMID 41126263

  15. 15

    Seizure evolution in a mouse model of West syndrome involves complex and time-dependent synapse remodeling, gliosis and alterations in lipid metabolism

    Ma R, Kang M, Kim GH, Kang H, Lee S, Yang Y, Lee HJ, Choi S, ..., Han K

    PLoS Biol, 2025 DOI PMID 41066510

  16. 16

    Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms

    Ahn W, Lee Y, Nam GH, You JB, Lee EJ

    Small Sci, 2025 DOI PMID 41256221

  17. 17

    TRPV1 inhibition sensitizes tumors to PD-1 blockade by reversing resistance to CTL-mediated killing

    Son MK, Lee HJ, Cho E, Oh SJ, Kim TW

    Sci Rep, 2025 DOI PMID 40594542

  18. 18

    Single-cell analysis reveals a longitudinal trajectory of meningioma evolution and heterogeneity

    Lee JY, Lee EJ, Seo BY, Kim J, Song Y, Lee D, Moon N, Koo H, ..., Sa JK

    Nat Commun, 2025 DOI PMID 40593590

  19. 19

    VHL-Mediated SYT11 Degradation Suppresses Gastric Cancer Cell Growth and Invasion Through Downregulation of SPINK1

    Yu JS, Hwang MA, Won M, Im JY, Kweon DH, Park YG, Kim BK

    J Cell Mol Med, 2025 DOI PMID 40576306

  20. 20

    Lysosomal targeting of liposomes with acidic pH and Cathepsin B induces protein aggregate clearance

    Jeon M, Kim DE, Choi SY, Kim S, Kim S, Lee H, Kim H

    Cell Commun Signal, 2025 DOI PMID 40537797

  21. 21

    Human Adipose Stem Cells Engineered to Express Carboxylesterase Confer Anti-Tumoral Efficacy of Irinotecan in Castration-Resistant Prostate Cancer Bone Metastasis Growth and Osteolysis

    Yun DH, Kim JH, Lee SH, Lee EJ, Park SI, Song YS

    World J Mens Health, 2025 DOI PMID 40583017

  22. 22

    Cytoplasmic WEE1 Promotes Resistance to PD-1 Blockade Through Hyperactivation of the HSP90A/TCL1/AKT Signaling Axis in NANOGhigh Tumors

    Kim S, Lee HJ, Lee S, Chung JE, Oh SJ, Song KH, Cho E, Son MK, ..., Kim TW

    Cancer Immunol Res, 2025 DOI PMID 40067354

  23. 23

    Targeted delivery of apelin using a novel extracellular vesicle platform for pulmonary arterial hypertension treatment

    Kim J, Choi YS, Kim J, Wahab R, Lee Y, Joo H, Park S, Lee I, ..., Kim IS

    Biomaterials, 2025 DOI PMID 40449081

  24. 24

    Development of a BMU-on-a-chip model based on spatiotemporal regulation of cellular interactions in the bone remodeling cycle

    Woo SM, Paek K, Yoon YM, Kim H, Park SI, Kim JA

    Mater Today Bio, 2025 DOI PMID 40206145

  25. 25

    Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure

    Kim S, Kim YK, Kim S, Choi YS, Lee I, Joo H, Kim J, Kwon M, ..., Kim IS

    Nat Commun, 2025 DOI PMID 39988725

  26. 26

    Controlled delivery of HIF-1α via extracellular vesicles with collagen-binding activity for enhanced wound healing

    Jeon S, Cho S, Yoo S, Lee Y, Goo J, Jeong YJ, Nam GH, Shin HT, ..., Kim IS

    J Control Release, 2025 DOI PMID 39921033

  27. 27

    Hierarchical protein nano-crystalline hydrogel with extracellular vesicles for ectopic lymphoid structure formation

    Ahn W, Han J, Kim N, Hwang YH, Kim W, Lee Y, Lee DY, Cheong IW, ..., Lee EJ

    Biomaterials, 2025 DOI PMID 39933315

  28. 28

    Ionic Diode-Based Drug Delivery System

    Yoo H, Kang SB, Kim J, Cho W, Ha H, Oh S, Jeong SH, Lee S, ..., Sun JY

    Adv Mater, 2024 DOI PMID 39718239

  29. 29

    Immunogenic clearance combined with PD-1 blockade elicits antitumor effect by promoting the recruitment and expansion of the effector memory-like CD8+T cell

    Kim SA, Kim S, Hong Y, Choi Y, Lee Y, Kwon M, Park SY, Jeong C, ..., Kim IS

    Transl Oncol, 2024 DOI PMID 39608213

  30. 30

    Transcriptomic analysis of cellular senescence induced by ectopic expression of ATF6α in human breast cancer cells

    Kim JW, Bae SH, Moon Y, Kim EK, Kim Y, Park YG, Han MR, Sohn J

    PLoS One, 2024 DOI PMID 39466820

  31. 31

    USF2 and TFEB compete in regulating lysosomal and autophagy genes

    Kim J, Yu YS, Choi Y, Lee DH, Han S, Kwon J, Noda T, Ikawa M, ..., Baek SH

    Nat Commun, 2024 DOI PMID 39333072

  32. 32

    Improvement of Therapeutic Effect via Inducing Non-Apoptotic Cell Death Using mRNA-Protection Nanocage

    Kim S, Kim S, Kim S, Lee NE, Lee SH, Kim H, Lee H

    Adv Healthc Mater, 2024 DOI PMID 39081097

  33. 33

    Novel insights into paclitaxel's role on tumor-associated macrophages in enhancing PD-1 blockade in breast cancer treatment

    Choi Y, Kim SA, Jung H, Kim E, Kim YK, Kim S, Kim J, Lee Y, ..., Kim IS

    J Immunother Cancer, 2024 DOI PMID 39009452

  34. 34

    The identification of effective tumor-suppressing neoantigens using a tumor-reactive TIL TCR-pMHC ternary complex

    Kim SH, Lee BR, Kim SM, Kim S, Kim MS, Kim J, Lee I, Kim HS, ..., Park WY

    Exp Mol Med, 2024 DOI PMID 38866910

  35. 35

    Novel Personalized Cancer Vaccine Using Tumor Extracellular Vesicles with Attenuated Tumorigenicity and Enhanced Immunogenicity

    Han J, Kim S, Hwang YH, Kim SA, Lee Y, Kim J, Cho S, Woo J, ..., Kim IS

    Adv Sci (Weinh), 2024 DOI PMID 38666427

  36. 36

    Targeted deletion of CD244 on monocytes promotes differentiation into anti-tumorigenic macrophages and potentiates PD-L1 blockade in melanoma

    Kim J, Kim TJ, Chae S, Ha H, Park Y, Park S, Yoon CJ, Lim SA, ..., Lee KM

    Mol Cancer, 2024 DOI PMID 38424542

  37. 37

    PPIB/Cyclophilin B expression associates with tumor progression and unfavorable survival in patients with pulmonary adenocarcinoma

    Hwang I, Song JS, Cho E, Song KH, Ra SH, Choi CM, Kim TW, Kim SH, Kim JW, Chung JY

    Am J Cancer Res, 2024 DOI PMID 38455410

  38. 38

    Angiogenesis-on-a-chip coupled with single-cell RNA sequencing reveals spatially differential activations of autophagy along angiogenic sprouts

    Lee S, Kim H, Kim BS, Chae S, Jung S, Lee JS, Yu J, Son K, ..., Jeon NL

    Nat Commun, 2024 DOI PMID 38172108

  39. 39

    Real-Time Live Imaging of Osteoclast Activation via Cathepsin K Activity in Bone Diseases

    Koo S, Lee EJ, Xiong H, Yun DH, McDonald MM, Park SI, Kim JS

    Angew Chem Int Ed Engl, 2023 DOI PMID 38105412

  40. 40

    Tm4sf19 deficiency inhibits osteoclast multinucleation and prevents bone loss

    Park S, Heo JS, Mizuno S, Kim M, An H, Hong E, Kang MG, Kim J, ..., Kim SJ

    Metabolism, 2023 DOI PMID 38016540

  41. 41

    Activation of Lysosomal Function Ameliorates Amyloid-β-Induced Tight Junction Disruption in the Retinal Pigment Epithelium

    Jo DH, Lee SH, Jeon M, Cho CS, Kim DE, Kim H, Kim JH

    Mol Cells, 2023 DOI PMID 37968982

  42. 42

    Suppression of the antitumoral activity of natural killer cells under indirect coculture with cancer-associated fibroblasts in a pancreatic TIME-on-chip model

    Kim HA, Kim H, Nam MK, Park JK, Lee MY, Chung S, Lee KM, Kuh HJ

    Cancer Cell Int, 2023 DOI PMID 37759302

  43. 43

    Five-Day Spacing of Two Fractionated Ablative Radiotherapies Enhances Antitumor Immunity

    Kim H, Lee E, Cho H, Kim E, Jang WI, Yang K, Lee YJ, Kim TJ, Kim MS

    Int J Radiat Oncol Biol Phys, 2023 DOI PMID 37717785

  44. 44

    G-Quadruplex-Filtered Selective Ion-to-Ion Current Amplification for Non-Invasive Ion Monitoring in Real Time

    Yoo H, Lee HR, Kang SB, Lee J, Park K, Yoo H, Kim J, Chung TD, ..., Oh SS

    Adv Mater, 2023 DOI PMID 37433455

  45. 45

    OR2H2 Activates CAMKKβ-AMPK-Autophagy Signaling Axis and Suppresses Senescence in VK2/E6E7 Cells

    Kim JM, Dziobaka S, Yoon YE, Lee HL, Jeong JH, Lee IR, Weidinger D, Yang C, ..., Lee SJ

    Pharmaceuticals (Basel), 2023 DOI PMID 37765029

  46. 46

    Inhibition of protein arginine deiminase II suppresses retinoblastoma in orthotopic transplantation in mice

    Kim S, Song YK, Cho CS, Kim HJ, Fang S, Jo DH, Kim H

    Oncol Rep, 2023 DOI PMID 37326108

  47. 47

    Harnessing Oncolytic Extracellular Vesicles for Tumor Cell-Preferential Cytoplasmic Delivery of Misfolded Proteins for Cancer Immunotherapy

    Kim GB, Kim S, Hwang YH, Kim S, Lee I, Kim SA, Goo J, Yang Y, ..., Kim IS

    Small, 2023 DOI PMID 37226374

  48. 48

    PHGDH preserves one-carbon cycle to confer metabolic plasticity in chemoresistant gastric cancer during nutrient stress

    Yoon BK, Kim H, Oh TG, Oh SK, Jo S, Kim M, Chun KH, Hwang N, ..., Fang S

    Proc Natl Acad Sci U S A, 2023 DOI PMID 37192160

  49. 49

    TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway

    Oh SJ, Lim JY, Son MK, Ahn JH, Song KH, Lee HJ, Kim S, Cho EH, ..., Kim TW

    Nat Commun, 2023 DOI PMID 37165076

  50. 50

    Mobilization of monocytic myeloid-derived suppressor cells is regulated by PTH1R activation in bone marrow stromal cells

    Lee EJ, Lee KJ, Jung S, Park KH, Park SI

    Bone Res, 2023 DOI PMID 37085481

  51. 51

    Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress

    Yu YS, Kim H, Kim KI, Baek SH

    Cell Death Differ, 2023 DOI PMID 36997734

  52. 52

    Circulating biomarkers for diagnosis and therapeutic monitoring in bone metastasis

    Song MK, Park SI, Cho SW

    J Bone Miner Metab, 2023 DOI PMID 36729305

  53. 53

    Small Extracellular Vesicles as a New Class of Medicines

    Lee I, Choi Y, Shin DU, Kwon M, Kim S, Jung H, Nam GH, Kwon M

    Pharmaceutics, 2023 DOI PMID 36839647

  54. 54

    Protein-based nanocages for vaccine development

    Kim SA, Lee Y, Ko Y, Kim S, Kim GB, Lee NK, Ahn W, Kim N, ..., Kim IS

    J Control Release, 2022 DOI PMID 36516900

  55. 55

    Nuclear transport of STAT6 determines the matrix rigidity dependent M2 activation of macrophages

    Kim JK, Han SB, Park SI, Kim IS, Kim DH

    Biomaterials, 2022 DOI PMID 36306683

  56. 56

    ROS inhibits RORα degradation by decreasing its arginine methylation in liver cancer

    Im H, Baek HJ, Yang E, Kim K, Oh SK, Lee JS, Kim H, Lee JM

    Cancer Sci, 2022 DOI PMID 36114756

  57. 57

    Flow cytometry-based immunophenotyping of myeloid-derived suppressor cells in human breast cancer patient blood samples

    Lee EJ, Jung S, Park KH, Park SI

    J Immunol Methods, 2022 DOI PMID 36058258

  58. 58

    NANOG confers resistance to complement-dependent cytotoxicity in immune-edited tumor cells through up-regulating CD59

    Son SW, Cho E, Cho H, Woo SR, Lee HJ, Oh SJ, Kim S, Kim JH, ..., Kim TW

    Sci Rep, 2022 DOI PMID 35606403

  59. 59

    PD-L1 siRNA-hyaluronic acid conjugate for dual-targeted cancer immunotherapy

    Kim S, Heo R, Song SH, Song KH, Shin JM, Oh SJ, Lee HJ, Chung JE, Park JH, Kim TW

    J Control Release, 2022 DOI PMID 35461969

  60. 60

    Targeting TCTP sensitizes tumor to T cell-mediated therapy by reversing immune-refractory phenotypes

    Lee HJ, Song KH, Oh SJ, Kim S, Cho E, Kim J, Park YG, Lee KM, ..., Kim TW

    Nat Commun, 2022 DOI PMID 35440620

  61. 61

    Lymph node fibroblastic reticular cells regulate differentiation and function of CD4 T cells via CD25

    Kim D, Kim M, Kim TW, Choe YH, Noh HS, Jeon HM, Kim H, Lee Y, ..., Lee SH

    J Exp Med, 2022 DOI PMID 35315876

  62. 62

    Targeting the NANOG/HDAC1 axis reverses resistance to PD-1 blockade by reinvigorating the antitumor immunity cycle

    Oh SJ, Lee HJ, Song KH, Kim S, Cho E, Lee J, Bosenberg MW, Kim TW

    J Clin Invest, 2022 DOI PMID 35104240

  63. 63

    PI3Kδ/γ inhibitor BR101801 extrinsically potentiates effector CD8+ T cell-dependent antitumor immunity and abscopal effect after local irradiation

    Yoon YN, Lee E, Kwon YJ, Gim JA, Kim TJ, Kim JS

    J Immunother Cancer, 2022 DOI PMID 35288465

  64. 64

    Regulation of autophagy by protein methylation and acetylation in cancer

    Jeon M, Park J, Yang E, Baek HJ, Kim H

    J Cell Physiol, 2021 DOI PMID 34237149

  65. 65

    Coordinated methyl readers: Functional communications in cancer

    Park IG, Jeon M, Kim H, Lee JM

    Semin Cancer Biol, 2021 DOI PMID 33753223